PUBLICATIONS
Journal Publications
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Laroy, M., Gsell, W., Himmelreich, D’Hooge, R., Van der Jeugd, A.
Isolation housing exacerbates Alzheimer's Disease phenotype in aged APP KI mice
Biorvx: BIORXIV/2019/777524. Submitted to Neurosci.
Poster and Oral Presentations
Ming-Sum, Yu., D’Hooge, R., Van der Jeugd, A.
MenoMouse: the relationship between menopause and dementia in a rodent study
Annual Meeting of the Belgian Association for
Psychological Sciences,
Université de Liège, Liège, Belgium, May 14th, 2019
POSTER PRESENTATION
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Ming-Sum, Yu., D'Hooge, R., Van der Jeugd, A.
Functional deficits in menopause-associated encephalopathy: a behavioural rodent study
Frontiers in Aging Neuroscience DOI: 10.3389/conf.fnins.2019.96.00043
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Rens, E., Rudi, D., Van der Jeugd, A.
Social isolation impacts late-life socio-cognitive decline in APP/PS1 mice.
Biorvx: BIORXIV/2019/777441. Submitted to JAD
Van der Jeugd, A., Kempen B., Hofbauer, L., Salazar, V., Seeuws, I., D’Hooge, R.
Effects of social isolation on social interaction behavior and ultrasonic vocalizations in adult female mice.
Federation of European Neuroscience Societies,
University of Belgrado, Belgrado, Serbia, July 10-13, 2019
POSTER PRESENTATION
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Van der Jeugd, A., Parra-Damas, A., Baeta-Corral, R., Soto-Faguás, C.M., Ahmed, T., LaFerla, F.M., Giménez-Llort, L., D’Hooge, R., Saura, C.A.
Reversal of memory and neuropsychiatric symptoms and reduced tau pathology by selenium in 3xTg-AD mice
Scientific Reports 8(1):6431
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Van der Jeugd, A., D'Hooge, R.
Assessment of Social Transmission of Food Preferences Behaviors
Journal of Visualized Experiments (131), e57029
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Stroobants, S., Damme, M., Van der Jeugd, A., Vermaercke, B., Andersson, C., Fogh, J., Saftig, P., Blanz, J., D'Hooge, R.
Long-term enzyme replacement therapy improves neurocognitive functioning and hippocampal synaptic plasticity in immune-tolerant alpha-mannosidosis mice
Neurobiology of Disease 106:255-268
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Nisbet R., Van der Jeugd A., Leinenga G., Evans H., Janowicz P., Gotz J
Combined effects of scanning ultrasound and a tau-specific single chain antibody in a tau transgenic mouse model
Brain 1;140(5):1220-1230
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Bodea L., Evans H., Van der Jeugd A., Ittner L., Delerue F., Kril J., Halliday G., Hodges J., Kiernan M., Gotz J
Accelerated aging exacerbates a pre-existing pathology in a tau transgenic mouse model
Aging Cell 16(2):377-386
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Van der Jeugd A., Vermaercke B., Halliday G., Staufenbiel M., Götz J
Impulsivity, decreased social exploration, and executive dysfunction in a mouse model of frontotemporal dementia
Neurobiology of Learning and Memory 130: 34-43
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Laurent C., Burnouf S., Ferry B., Batalha V., Coelho J., Baqi Y., Malik E., Mariciniak E., Parrot S., Van der Jeugd A., Faivre E., Flaten V., Ledent C., D'Hooge R., Sergeant N., Hamdane M., Humez S., Mueller C., Lopes L., Buee L., Blum D
A(2A) adenosine receptor deletion is protective in a mouse model of Tauopathy
Molecular Psychiatry 21 (1): 97-107
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Pooters T.*, Van der Jeugd A.*, Callaerts-Vegh Z., D'Hooge R. (*joint 1st)
Telencephalic neurocircuitry and synaptic plasticity in rodent spatial learning and memory
Brain Research 1621: 294-308
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Van der Jeugd, A., D’Hooge, R.
Social Transmission of Food Preferences
FENS/Hertie Winter School, Universitatszentrum Obergurgl, Austria, January 10, 2019
ORAL PRESENTATION
Van der Jeugd, A., Parra-Damas, A., Baeta-Corral, R., Soto-Faguás, C.M., Ahmed, T., LaFerla, F.M., Giménez-Llort, L., D’Hooge, R., Saura, C.A.
Reversal of memory and neuropsychiatric symptoms and reduced tau pathology by selenium in 3xTg-AD mice
Annual meeting of the Society for Neuroscience, San, Diego (CA), USA, 3-7 November, 2018
ORAL PRESENTATION
Van der Jeugd A., D'Hooge R.
Only the lonely? The relationship between social isolation and dementia
National Congress of the Belgian Society of Neuroscience, Ghent, Belgium, November 22, 2017
POSTER PRESENTATION
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Van der Jeugd A., Bloemen I., Kara F., Shah D., Van der Linden A., D'Hooge R. The olfactory system and its relevance for behavioral screening and diagnostic imaging in neurological disorders
Annual Meeting of the Society for Neuroscience, San Diego (CA), USA, 11-16 November, 2016
POSTER PRESENTATION
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Gotz J., Leinenga G., Nisbet R., Van der Jeugd A., Robert H.
Scanning ultrasound as a treatment tool of proteinopathies including Alzheimer's disease
Annual meeting of the Society for Neuroscience, San Diego (CA), USA, 11-16 November, 2016
ORAL PRESENTATION
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Leinenga G., Nisbet R., Hatch R., Van der Jeugd A., Evans H., Gotz J.
Scanning focused ultrasound disruption of the blood-brain barrier as an Alzheimer's disease therapy
International Symposium on Focused Ultrasound, North Bethesda, MD, USA, 28 August- 1 September, 2016
POSTER PRESENTATION
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Van der Jeugd, A.
Mouse behavior in preclinical Alzheimer research: Challenges and Opportunities
Annual meeting of the Belgian Association for Psychological Science, Thomas More College, Antwerp, Belgium, May 24, 2016.
ORAL PRESENTATION
Ahmed T., Van der Jeugd A., Blum D., Galas M., D'Hooge R., Buee L., Balschun D
Cognition and hippocampal synaptic plasticity in mice with a homozygous tau deletion
Neurobiology of Aging 35 (11): 2474-8
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Van der Jeugd A., Vermaercke B., Derisbourg M., Lo A., Hamdane M., Blum D., Buée L., D'Hooge R
Progressive Age-Related Cognitive Decline in Tau Mice
Journal of Alzheimer's Disease 37 (4): 777-788
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Van der Jeugd A., Blum D., Raison S., Eddarkaoui S., Buée L., D'Hooge R
Observations in THY-Tau22 mice that resemble behavioral and psychological signs and symptoms of dementia
Behavioural Brain Research 34-39
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Van der Jeugd A., Hochgräfe K., Ahmed T., Decker J., Sydow A., Hofmann A., Wuyts D., Messing L., Balschun D., D'Hooge R., Mandelkow E.
Cognitive defects are reversible in inducible mice expressing pro-aggregant full-length human Tau
Acta Neuropathologica. 123 (6): 787-805
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Sydow A., Van der Jeugd A., Zheng F., Ahmed T., Balschun D., Petrova O., Drexler D., Zhou L., Rune G., Mandelkow E., D'Hooge R., Alzheimer C., Mandelkow E.
Reversibility of Tau-Related Cognitive Defects in a Regulatable FTD Mouse Model
Journal of Molecular Neuroscience 45 (3): 432-437
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Van der Jeugd A., Ahmed T., Burnouf S., Belarbi K., Hamdame M., Grosjean M., Humez S., Balschun D., Blum D., Buée L., D'Hooge R.
Hippocampal tauopathy in tau transgenic mice coincides with impaired hippocampus-dependent learning and memory, and attenuated late-phase long-term depression of synaptic transmission
Neurobiology of Learning and Memory 95 (3): 296-304
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Sydow A.*, Van der Jeugd A.*, Zheng F., Ahmed T., Balschun D., Petrova O., Drexler D., Zhou L., Rune G., Mandelkow E., D'Hooge R., Alzheimer C., Mandelkow E. (*joint 1st)
Tau-Induced Defects in Synaptic Plasticity, Learning, and Memory Are Reversible in Transgenic Mice after Switching Off the Toxic Tau Mutant
Journal of Neuroscience 31 (7): 2511-2525
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Buee L., Troquier L., Burnouf S., Belarbi K., Van der Jeugd A., Ahmed T., Fernandez-Gomez F., Caillierez R., Grosjean M., Begard S., Bardot B., Demeyer D., Obriot H., Brion I., Buee-Scherrer V., Maurage C., Balschun D., D'Hooge R., Hamdane M., Blum D., Sergeant N.
From tau phosphorylation to tau aggregation: what about neuronal death?
Biochemical Society Transactions 38 (4): 967-972
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Van der Jeugd, A.; Nisbet, R.; Leinega, G.; Götz, J.
Focused ultrasound opens blood-brain-barrier and improves pathologic abnormalities and behaviour in a mouse model of Alzheimer's disease
Journal of Neurochemistry. vol.134 (Special issue) 25th Biennial Meeting of the International Society for Neurochemistry Jointly with the 13th Meeting of the Asian Pacific Society for Neurochemistry in Conjunction with the 35th Meeting of the Australasian Neuroscience Society, Cairns, Australia, August 23-27, 2015
POSTER PRESENTATION
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Götz J., Nisbet R., Leinga G., Van der Jeugd A.
Novel strategies to target tau and Ab toxicity
Journal of Neurochemistry. vol.134 (Special issue) 25th Biennial Meeting of the International Society for Neurochemistry Jointly with the 13th Meeting of the Asian Pacific Society for Neurochemistry in Conjunction with the 35th Meeting of the Australasian Neuroscience Society, Cairns, Australia, August 23-27, 2015
ORAL PRESENTATION
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Van der Jeugd A., Ahmed T., Balschun D., D'Hooge R.
Cognitive deficits and synaptic dysfunction in mouse models of Alzheimer’s disease
Annual meeting of the Belgian Association for Psychological Science, Leuven, Belgium, May 27, 2014
POSTER PRESENTATION
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Menigoz A., Ahmed T., Sabanov V., Vinken K., Van der Jeugd A., Pinto S., Kerselaers S., Segal A., Freichel M., Flockerzi V., Voets T., D'Hooge R., Nilius B., Vennekens R., Balschun D.
TRPM4 is a key mediator for NMDA-receptor dependent hippocampal LTP but not LTD
LIND seminar, Mechelen, Belgium, December 5, 2014
POSTER PRESENTATION
Van der Jeugd A., Ahmed T., Brouillette J., Blum D., Buée L., Balschun D., D'Hooge R.
​Minor Behavioural Deficits and Evidence for Altered Longterm Potentiation of Synaptic Transmission in Tau Knockout Mice
International Conference AD/PD, Florence, Italy, 6-10 March, 2013
POSTER PRESENTATION
Van der Jeugd A., Lo A., Belarbi K., Hamdame M., Blum D., Buée L., D'Hooge R.
Behavioural effects of selenium in mouse models of Alzheimer's disease
International Stockholm/Springfield Symposium on Advances in Alzheimer Therapy, Stockholm, Sweden, 9-12 May 2012
POSTER PRESENTATION
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Van der Jeugd A., Raison S., Belarbi K., Hamdame M., Grosjean M., Humez S., Blum D., Buée L., Balschun D., D'Hooge R.
Non-cognitive behaviours in a Tau transgenic model of Alzheimer's disease
AD/PD, Barcelona, Spain, 9-13 March 2011
POSTER PRESENTATION
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Van der Jeugd A., Ahmed T., D'Hooge R., Balschun D.
Age-related effects on hippocampal synaptic metaplasticity in C57BL/6 wild type mice
Belgian Society for Neuroscience, KU Leuven, Leuven, Belgium, 23 May, 2011
ORAL PRESENTATION
Van der Jeugd A., Goddyn H., Laeremans A., Arckens L., D'Hooge R., Verguts T.
Hippocampal involvement in the acquisition of relational associations, but not in the expression of a transitive inference task in mice
Behavioral Neuroscience 123 (1): 109-114
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Van der Jeugd A., Ahmed T., Brouillette J., Blum D., Buée L., Balschun D., D'Hooge R.
No behavioral deficits but evidence for altered late-phase long-term potentiation of synaptic transmission in Tau knockout mice
FENS Forum of European Neuroscience, Amsterdam,
the Netherlands, 3-7 July, 2010
POSTER PRESENTATION
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Martire A., Burnouf S., Laurent C., Muhr-Tailleux A., Van der Jeugd A., Leboucher A., Fernandez-Gomez F., Troquier L., Grosjean M., Demeyer D., Brion J., Buisson A., D'Hooge R., Sergeant N., Humez S., Hamdane M., Popoli P., Buée L., Blum D., Belarbi K
Impairment of BDNF-mediated hippocampal synaptic facilitation in a transgenic model of Alzheimer's disease-like Tau pathology
FENS Forum of European Neuroscience, Amsterdam, the Netherlands, 3-7 July, 2010
POSTER PRESENTATION
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Van der Jeugd A., Ahmed T., Burnouf S., Belarbi K., Hamdame M., Grosjean M., Humez S., Balschun D., Blum D., Buee L., D'Hooge R.
Impaired hippocampus-dependent learning coincides with attenuated late-phase long-term depression of synaptic transmission in tau mutant mice
Annual Meeting of the Society for Neuroscience, Chicago, USA, 17-21 October, 2009
POSTER PRESENTATION
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Brouillette J., Kuperstein I., Ahmed T., Van der Jeugd A., Burnouf S., Belarbi K., Blum D., Balschun D., D'Hooge R., De Strooper B., Buee L.
Tau experimental models: effects of amyloid beta oligomers on tau pathology
Official Symposium of the 9th International Conference AD/PD, Prague, Czech, 11-15 March, 2009
ORAL PRESENTATION
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Van der Jeugd A., D'Hooge R., Balschun D., Ahmed T.
Memory defects in transgenic tau mice
Annual meeting of the Belgian Association for Psychological Science. KU Leuven, Leuven, Belgium, May 26, 2008
POSTER PRESENTATION